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81.
An improved algorithm for the shallow water equations model reduction: Dynamic Mode Decomposition vs POD 下载免费PDF全文
We propose an improved framework for dynamic mode decomposition (DMD) of 2‐D flows for problems originating from meteorology when a large time step acts like a filter in obtaining the significant Koopman modes, therefore, the classic DMD method is not effective. This study is motivated by the need to further clarify the connection between Koopman modes and proper orthogonal decomposition (POD) dynamic modes. We apply DMD and POD to derive reduced order models (ROM) of the shallow water equations. Key innovations for the DMD‐based ROM introduced in this paper are the use of the Moore–Penrose pseudoinverse in the DMD computation that produced an accurate result and a novel selection method for the DMD modes and associated amplitudes and Ritz values. A quantitative comparison of the spatial modes computed from the two decompositions is performed, and a rigorous error analysis for the ROM models obtained is presented. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
82.
Modified extended BDF scheme for the discontinuous Galerkin solution of unsteady compressible flows 下载免费PDF全文
In this paper, a high‐order DG method coupled with a modified extended backward differentiation formulae (MEBDF) time integration scheme is proposed for the solution of unsteady compressible flows. The objective is to assess the performance and the potential of the temporal scheme and to investigate its advantages with respect to the second‐order BDF. Furthermore, a strategy to adapt the time step and the order of the temporal scheme based on the local truncation error is considered. The proposed DG‐MEBDF method has been evaluated for three unsteady test cases: (i) the convection of an inviscid isentropic vortex; (ii) the laminar flow around a cylinder; and (iii) the subsonic turbulent flow through a turbine cascade. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
83.
Rose Mary Michell Iwona Blaszczyk‐Lezak Carmen Mijangos Alejandro J. Müller 《Journal of Polymer Science.Polymer Physics》2014,52(18):1179-1194
In this article, a review of recent literature on confined crystallization within nanoporous anodic aluminum oxide (AAO) templates is presented. For almost all infiltrated polymeric materials, crystal orientation within the nanopores is a function of pore diameter. Tc and Tm usually decrease and are a function of pore size. When no pore interconnection remains, the crystallization occur at large supercoolings in heterogeneity free environments. Hence, the nucleation mechanism changes from heterogeneous to surface or homogeneous nucleation. The crystallization kinetics of infiltrated polymers should be close to first order, since in confined environments nucleation is the determining step of the overall crystallization and Avrami indexes (n) of ~1 (or lower in some cases) should be obtained. Examples are provided where these conditions have been met and first order kinetics (n = 1) were measured as opposed to higher orders (n = 3?4) for the same polymer in the bulk. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2014 , 52, 1179–1194 相似文献
84.
A simple, highly efficient synthetic protocol is developed for the synthesis of unsymmetrical diaryl vinyl selenides from diaryldiselenide and β-bromo styrene under transition-metal free conditions in N,N′-dimethyl propylene urea and 130 °C to afford high yields and excellent selectivities. This method provides a new strategy to fabricate a wide variety of important substituted molecular skeletons and an alternative to conventionally used metal salts, additives, and ligands. 相似文献
85.
Measurement of Large Dipolar Couplings of a Liquid Crystal with Terminal Phenyl Rings and Estimation of the Order Parameters 下载免费PDF全文
NMR spectroscopy is a powerful means of studying liquid‐crystalline systems at atomic resolutions. Of the many parameters that can provide information on the dynamics and order of the systems, 1H–13C dipolar couplings are an important means of obtaining such information. Depending on the details of the molecular structure and the magnitude of the order parameters, the dipolar couplings can vary over a wide range of values. Thus the method employed to estimate the dipolar couplings should be capable of estimating both large and small dipolar couplings at the same time. For this purpose, we consider here a two‐dimensional NMR experiment that works similar to the insensitive nuclei enhanced by polarization transfer (INEPT) experiment in solution. With the incorporation of a modification proposed earlier for experiments with low radio frequency power, the scheme is observed to enable a wide range of dipolar couplings to be estimated at the same time. We utilized this approach to obtain dipolar couplings in a liquid crystal with phenyl rings attached to either end of the molecule, and estimated its local order parameters. 相似文献
86.
High‐performance liquid chromatographic column packings with different particle sizes: Chromatographic behavior for the quality analysis of HuanglianShangqing pill 下载免费PDF全文
Dongzhi Yang Ying Li Fangxiu Yang Yan Du Yinjie Li Xiaoxiao Zheng Daoquan Tang 《Journal of separation science》2015,38(3):381-389
The chromatographic separation of traditional Chinese medicines is still a highly challenging task in analytical science with respect to its hundreds and thousands of chemical compounds, while increase of separation efficiency can greatly improve the separation power of chromatographic column for traditional Chinese medicine. In this study, 13 bioactive components in HuanglianShangqing pill were selected as an index to optimize the separation conditions and evaluate the system suitability of three commercially available columns packed with 1.8, 3.5, and 5.0 μm particles. The chromatographic separations were obtained by the most appropriate Eclipse Plus C18 column (100 × 2.1 mm, 3.5 μm) within 45 min using gradient elution with aqueous‐ammonium acetate (10 mmol/L, pH 5.0) and acetonitrile, at a flow rate of 0.3 mL/min and an operating temperature of 30°C. The quality of HuanglianShangqing pill was assessed through combining simultaneous quantification of 13 compounds with fingerprint analysis. For the qualitative analysis, mass spectrometry was used to confirm the 13 compounds. All the validation data conformed to the acceptable requirements. For the fingerprint analysis, 32 peaks were selected as the common peaks at 254 nm to evaluate the similarities among HuanglianShangqing pills obtained from ten manufacturers. 相似文献
87.
Ultrasound‐assisted emulsification microextraction coupled with high‐performance liquid chromatography for the simultaneous determination of fragrance allergens in cosmetics and water 下载免费PDF全文
Jessica Pérez‐Outeiral Esmeralda Millán Rosa Garcia‐Arrona 《Journal of separation science》2015,38(9):1561-1569
A simple, inexpensive, and environmentally friendly method based on ultrasound‐assisted emulsification microextraction followed by solidification of floating organic drop and high‐performance liquid chromatography coupled to diode array detection was developed for the simultaneous determination of 18 potentially allergenic fragrance substances. Several parameters affecting the microextraction process were investigated in detail by the “one‐variable‐at‐a‐time” approach. Optimal conditions were the following: 50 μL of 2‐dodecanol as extraction solvent, 10 mL of sample containing 150 g/L of salt, and 5 min of sonication at 35°C. Under the optimized conditions, method showed good linearity in the selected ranges, with squared correlation coefficients ranging from 0.948 to 0.999. Limits of detection ranged from 0.001 to 0.154 μg/mL and enrichment factors from 9 to 237. Precision of the method, expressed as relative standard deviation, was checked at two levels obtaining good results (3.3–14.4%). Recovery studies were made in baby bath water and in eau de cologne showing acceptable accuracy. Finally, the developed method was successfully applied to different commercial cosmetic and water samples. The most commonly found analyte was linalool followed by cinnamal and lilial. Most of the analyzed samples contained at least one of the target compounds. 相似文献
88.
Chromatographic enantioseparations on the order of a few seconds can be achieved by supercritical fluid chromatography using short columns packed with chiral stationary phases. The evolution of ‘world record’ speeds for the chromatographic separation of enantiomers has steadily dropped from an industry standard of 20–40 min just two decades ago, to a current ability to perform many enantioseparations in well under a minute. Improvements in instrument and column technologies enabled this revolution, but the ability to predict optimal separation time from an initial method development screening assay using the tmin cc predictor greatly simplifies the development and optimization of high‐speed chiral chromatographic separations. In this study, we illustrate how the use of this simple tool in combination with the workhorse technique of supercritical fluid chromatography on customized short chiral columns (1–2 cm length) allows us to achieve ultrafast enantioseparations of pharmaceutically relevant compounds on the 5–20 s scale, bringing the technique of high‐throughput enantiopurity analysis out of the specialist realm and into the laboratories of most researchers. 相似文献
89.
Determination of phthalate esters from environmental water samples by micro‐solid‐phase extraction using TiO2 nanotube arrays before high‐performance liquid chromatography 下载免费PDF全文
We describe a highly sensitive micro‐solid‐phase extraction method for the pre‐concentration of six phthalate esters utilizing a TiO2 nanotube array coupled to high‐performance liquid chromatography with a variable‐wavelength ultraviolet visible detector. The selected phthalate esters included dimethyl phthalate, diethyl phthalate, dibutyl phthalate, butyl benzyl phthalate, bis(2‐ethylhexyl)phthalate and dioctyl phthalate. The factors that would affect the enrichment, such as desorption solvent, sample pH, salting‐out effect, extraction time and desorption time, were optimized. Under the optimum conditions, the linear range of the proposed method was 0.3–200 μg/L. The limits of detection were 0.04–0.2 μg/L (S/N = 3). The proposed method was successfully applied to the determination of six phthalate esters in water samples and satisfied spiked recoveries were achieved. These results indicated that the proposed method was appropriate for the determination of trace phthalate esters in environmental water samples. 相似文献
90.
High‐throughput salting‐out‐assisted liquid–liquid extraction for the simultaneous determination of atorvastatin,ortho‐hydroxyatorvastatin,and para‐hydroxyatorvastatin in human plasma using ultrafast liquid chromatography with tandem mass spectrometry 下载免费PDF全文
Yong Yang Qiufang Xu Lei Zhou Dafang Zhong Xiaoyan Chen 《Journal of separation science》2015,38(6):1026-1034
A high‐throughput, specific, and rapid liquid chromatography with tandem mass spectrometry method was established and validated for the simultaneous determination of atorvastatin and its two major metabolites, ortho‐hydroxyatorvastatin and para‐hydroxyatorvastatin, in human plasma. A simple salting‐out‐assisted liquid–liquid extraction using acetonitrile and a mass‐spectrometry‐friendly salt, ammonium acetate, was employed to extract the analytes from human plasma. A recovery of more than 81% for all analytes was achieved in 1 min extraction time. Chromatographic separation was performed on a Kinetex XB C18 column utilizing a gradient elution starting with a 60% of water solution (1% formic acid), followed by increasing percentages of acetonitrile. Analytes were detected on a tandem mass spectrometer equipped with an electrospray ionization source that was operated in the positive mode, using the transitions of m/z 559.3 → m/z 440.2 for atorvastatin, and m/z 575.3 → m/z 440.2 for both ortho‐ and para‐hydroxyatorvastatin. Deuterium‐labeled compounds were used as the internal standards. The method was validated over the concentration ranges of 0.0200–15.0 ng/mL for atorvastatin and ortho‐hydroxyatorvastatin, and 0.0100–2.00 ng/mL for para‐hydroxyatorvastatin with acceptable accuracy and precision. It was then successfully applied in a bioequivalence study of atorvastatin. 相似文献